Garcinia cambogia: Does it work?
Onakpoya, I. Journal of Obesity, 2011.
NYU Langone Medical Center: «Weight Loss Aids.»
Byrne, S. Consumer Reports, March 24, 2014.
Wielinga, P.Y. American Journal of Physiology, June 1, 2005.
Leonhardt, M. Nutrition, October 2004.
Hayamizu, K. Fitoterapia, April 2003.
Preuss, H. Nutrition Research, January 2004.
Preuss, H. Diabetes, Obesity and Metabolism, May 2004.
Preuss, H. International Journal of Clinical Pharmacology Research, February 2005.
Drugs.com: «Garcinia (hydroxycitric acid).»
Kim, Y. World Journal of Gastroenterology, Aug. 7, 2013.
Stohs, S. Toxicology Mechanisms and Methods, November 2010.
Clouatre, D. World Journal of Gastroenterology, Nov. 28, 2013.
Marquez, F. Critical Reviews in Food Science and Nutrition, Issue 7, 2012.
Medscape: «Leukotriene Receptor Antagonists.»
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Garcinia cambogia is hot. Nearly a million Americans each month Google this supposed weight-loss supplement. They’re looking for reviews on garcinia cambogia’s effectiveness, what kind of side effects it causes, and where they can buy it. My mom recently bought a bottle of the pills at Costco because she saw a segment about garcinia cambogia on a TV show.
Manufacturers claim that garcinia cambogia boosts weight loss by, among other things, «slowing the body’s ability to absorb fat,» «replacing fat with toned muscles,» and even improving your mood and suppressing «the drive to react to stressful situations with food.» How, you may ask? It’s mostly pinned on hydroxycitric acid (HCA), a substance found in garcinia cambogia that appears to inhibit an enzyme called citrate lyase and interferes with fatty acid metabolism.
“HCA does do that—but in a petri dish,» says Steven Heymsfield, M.D., the former head of the Pennington Biomedical Research Center in Baton Rouge, La. «Converting that to actual weight loss in humans would take 1,000 steps beyond that,» he says.
Back in 1998, Heymsfield published the first randomized controlled trial on the effectiveness of garcinia cambogia, in the Journal of the American Medical Association. He found no weight-loss benefits. Heymsfield, who continues to study the topic of weight-loss supplements at Pennington, says that about a dozen negative studies have since been published about garcinia cambogia. But that has not stopped marketers of the supplement, he says, from “weaving a story with obscure facts. Maybe each fragment has some validity, but if you wind it together it makes no sense at all.”
Fat burners are generally some combination of herb-derived stimulants, essential fatty acids, chromium picolinate, pyruvate, and/or hydroxycitric acid.
Herb-derived stimulants include caffeine and ephedrine as well as the herbs guarana and ma huang. Two or three of these stimulants are usually ‘stacked’ together in one weight loss product, often along with aspirin or willow bark. They are supposed to increase energy while stimulating fat burning. Most experts agree they do work when combined with exercise. Their safety, however, is another matter.
«Ephedra [which comes from ma huang] is effective … particularly when combined with aspirin and other ingredients,» says Heymsfield. «But it raises blood pressure and can cause fatal heart attacks, [heart] arrhythmias, and strokes. … The ads are very deceptive for ma huang regarding safety.»
Klauer and colleagues studied the weight loss potential of ephedra last year. «People did lose more weight with it,» she says, «but their elevations in blood pressure remained high even after they stopped the drug. … So, I really don’t recommend ephedra.»
According to Klauer, both ephedra and caffeine work by increasing your resting metabolic rate, which can be done more safely and cheaply simply by exercising more and eating less.
Despite a family history of heart disease, would-be triathlete Matthew Martin chose a combination of caffeine and ephedrine as his fat-burning program. He did notice his heart rate speed up after he popped a pill, but it didn’t bother him. He found that taking the pills boosted his energy enough to make him want to work out more and reach his fitness goals sooner. One month after stopping the program, he remains in good shape, but he’s also still in full-blown triathlon training.
Essential fatty acids include conjugated linoleic acid (CLA) and flax seed oil. They are sometimes used in combination with garlic to increase muscle mass and burn fat. They seem to be helpful in animals, and some new research is showing promise in humans.
Michael W. Pariza, PhD, director of the Food Research Institute at the University of Wisconsin in Madison, has studied CLA. «The clinical evidence is certainly emerging that it can be helpful, particularly in controlling fat and weight gain,» he tells WebMD. «We also have pretty good evidence that it relieves a lot of the adverse effects [such as dizziness and stomach problems] that people have when they are dieting.»
If you have been searching for the efficient, affordable, and harmless weight-loss solution, then Garcinia Extra is just the thing for you. Anyone can lose a weight, but only very few can lose it in a natural and safe way. This is what Garcinia Extra is all about. Here’s how this supplement gets down to work:
The users of Garcinia Extra have reported that this supplement has been able to suppresses their appetite by increasing their serotonin levels. You should know that insuficient serotonin levels are associated with anxiety and depression. The moment your serotonin level start rising, your mood will improve. As a result, you won’t feel the need to eat whenever you are experiencing emotional issues.
The other ingredient HCA (hydroxycitric acid) is a definitive must-have if you want to prevent the process of fat-making. How? Well, thanks to this ingredient you are inhibiting a key enzyme (citrate lyase), which transforms your carbohydrates into fat.
The best thing you can do for your metabolism is to add Garcinia Extra to your daily diet and exercise routine. When your metabolism works properly, you will never experience the shortage of energy and fatigue. In addition, Garcinia Cambogia Extra review can help you optimise your body’s cholesterol balance. You should know that the ingridients of this supplement can do a lot in lowering yourbad cholesterol (LDL) and increasing your good cholesterol (HDL) levels. So, you don’t have to worry about heart attacks and strokes. Finally, you will be able to lower your blood pressure.
The HCA included in Garcinia Extra’s formula is directly associated with our body’s cortisol levels. What’s that? Well, this is one of the most common stress hormones. If you can decrease your stress hormone levels, then you can control your anxiety.
Hydroxycut: Does it work? Is it Safe?
Said, O. The Open Complementary Medicine Journal, 2010.
FDA: «Questions and Answers: Hydroxycut;» «Warning on Hydroxycut Products;» and «Beware of Fraudulent Weight-Loss ‘Dietary Supplements.'»
Antaki Center for Herbal Medicine.
Phytotherapie, November 2006.
John Doherty, director of regulatory affairs, Iovate Health Sciences International.
Vinson, J. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2012.
Watanabe, T. Clinical and Experimental Hypertension, July 2006.